Entity Details

Primary name AL1A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00352
EntryNameAL1A1_HUMAN
FullNameRetinal dehydrogenase 1
TaxID9606
Evidenceevidence at protein level
Length501
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesALDH1A1

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0001758 retinal dehydrogenase activity
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0005096 GTPase activator activity
GO:0005497 androgen binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006069 ethanol oxidation
GO:0006081 cellular aldehyde metabolic process
GO:0018479 benzaldehyde dehydrogenase (NAD+) activity
GO:0042572 retinol metabolic process
GO:0051287 NAD binding
GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
GO:0070062 extracellular exosome
GO:0120163 negative regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR015590 Aldehyde dehydrogenase domainDomainDomain
IPR016160 Aldehyde dehydrogenase, cysteine active siteSiteConserved site
IPR016161 Aldehyde/histidinol dehydrogenaseFamilyHomologous superfamily
IPR016162 Aldehyde dehydrogenase, N-terminalFamilyHomologous superfamily
IPR016163 Aldehyde dehydrogenase, C-terminalFamilyHomologous superfamily
IPR029510 Aldehyde dehydrogenase, glutamic acid active siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00162 Vitamin ADrugbanksmall molecule
DB00755 TretinoinDrugbanksmall molecule
DB04447 1,4-DithiothreitolDrugbanksmall molecule
DB09462 GlycerinDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink