Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Accession	P00367
EntryName	DHE3_HUMAN
FullName	Glutamate dehydrogenase 1, mitochondrial
TaxID	9606
Evidence	evidence at protein level
Length	558
SequenceStatus	complete
DateCreated	1986-07-21
DateModified	2021-06-02

Genes

GLUD1

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GO	Name
GO:0004352	glutamate dehydrogenase (NAD+) activity
GO:0004353	glutamate dehydrogenase [NAD(P)+] activity
GO:0004354	glutamate dehydrogenase (NADP+) activity
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005783	endoplasmic reticulum
GO:0006537	glutamate biosynthetic process
GO:0006538	glutamate catabolic process
GO:0006541	glutamine metabolic process
GO:0009064	glutamine family amino acid metabolic process
GO:0021762	substantia nigra development
GO:0032024	positive regulation of insulin secretion
GO:0042802	identical protein binding
GO:0043531	ADP binding
GO:0070403	NAD+ binding
GO:0070728	leucine binding
GO:0072350	tricarboxylic acid metabolic process

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Subcellular Location
Endoplasmic reticulum
Mitochondrion

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Domain	Name	Category	Type
IPR006095	Glutamate/phenylalanine/leucine/valine dehydrogenase	Family	Family
IPR006096	Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal	Domain	Domain
IPR006097	Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain	Domain	Domain
IPR033524	Leu/Phe/Val dehydrogenases active site	Site	Active site
IPR033922	NAD(P) binding domain of glutamate dehydrogenase	Domain	Domain
IPR036291	NAD(P)-binding domain superfamily	Family	Homologous superfamily

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Drug	Name	Source	Type
DB00142	Glutamic acid	Drugbank	small molecule
DB00157	NADH	Drugbank	small molecule
DB00756	Hexachlorophene	Drugbank	small molecule
DB04137	Guanosine-5'-Triphosphate	Drugbank	small molecule
DB11081	Aluminum chloride	Drugbank	small molecule

0 interactions

Interactor	Partner	Sources	Publications	Link