Entity Details

Primary name CERU_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00450
EntryNameCERU_HUMAN
FullNameCeruloplasmin
TaxID9606
Evidenceevidence at protein level
Length1065
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCP

GO terms

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GOName
GO:0004322 ferroxidase activity
GO:0005507 copper ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005765 lysosomal membrane
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0006825 copper ion transport
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
GO:0016491 oxidoreductase activity
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0051087 chaperone binding
GO:0055072 iron ion homeostasis
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001117 Multicopper oxidase, type 1DomainDomain
IPR002355 Multicopper oxidase, copper-binding siteSiteBinding site
IPR008972 CupredoxinFamilyHomologous superfamily
IPR011706 Multicopper oxidase, C-terminalDomainDomain
IPR011707 Multicopper oxidase, N-termianlDomainDomain
IPR033138 Multicopper oxidases, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB01373 CalciumDrugbanksmall molecule
DB01592 IronDrugbanksmall molecule
DB01593 ZincDrugbanksmall molecule
DB06778 Cupric sulfateSwissprotsmall molecule
DB09130 CopperDrugbanksmall molecule
DB11134 Cupric oxideSwissprotsmall molecule
DB12965 SilverDrugbanksmall molecule
DB13257 Ferrous sulfate anhydrousDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14488 Ferrous gluconateDrugbanksmall molecule
DB14489 Ferrous succinateDrugbanksmall molecule
DB14490 Ferrous ascorbateDrugbanksmall molecule
DB14491 Ferrous fumarateDrugbanksmall molecule
DB14501 Ferrous glycine sulfateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink