Entity Details

Primary name PGK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00558
EntryNamePGK1_HUMAN
FullNamePhosphoglycerate kinase 1
TaxID9606
Evidenceevidence at protein level
Length417
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesPGK1

GO terms

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GOName
GO:0004618 phosphoglycerate kinase activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0016020 membrane
GO:0016310 phosphorylation
GO:0016525 negative regulation of angiogenesis
GO:0030855 epithelial cell differentiation
GO:0031639 plasminogen activation
GO:0043531 ADP binding
GO:0044003 modulation by symbiont of host process
GO:0045121 membrane raft
GO:0047134 protein-disulfide reductase (NAD(P)) activity
GO:0061621 canonical glycolysis
GO:0070062 extracellular exosome
GO:0071456 cellular response to hypoxia

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001576 Phosphoglycerate kinaseFamilyFamily
IPR015824 Phosphoglycerate kinase, N-terminalFamilyHomologous superfamily
IPR015911 Phosphoglycerate kinase, conserved siteSiteConserved site
IPR036043 Phosphoglycerate kinase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00709 LamivudineDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]TriphosphateDrugbanksmall molecule
DB04510 3-phospho-D-glyceric acidDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PGK1_HUMANMK13_MOUSEBioGRID19135240 details