Entity Details

Primary name CFAD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00746
EntryNameCFAD_HUMAN
FullNameComplement factor D
TaxID9606
Evidenceevidence at protein level
Length253
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCFD

GO terms

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GOName
GO:0002576 platelet degranulation
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0006508 proteolysis
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0007219 Notch signaling pathway
GO:0008236 serine-type peptidase activity
GO:0031093 platelet alpha granule lumen
GO:0034774 secretory granule lumen
GO:0043312 neutrophil degranulation
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR037561 Complement factor DFamilyFamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03058 2-Aminobenzyl alcoholDrugbanksmall molecule
DB04459 3,4-DichloroisocoumarinDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink