Entity Details

Primary name PLMN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00747
EntryNamePLMN_HUMAN
FullNamePlasminogen
TaxID9606
Evidenceevidence at protein level
Length810
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesPLG

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0010812 negative regulation of cell-substrate adhesion
GO:0022617 extracellular matrix disassembly
GO:1990405 protein antigen binding
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0008236 serine-type peptidase activity
GO:0031093 platelet alpha granule lumen
GO:0051087 chaperone binding
GO:0051702 biological process involved in interaction with symbiont
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:0004175 endopeptidase activity
GO:0008285 negative regulation of cell population proliferation
GO:0019900 kinase binding
GO:0031232 extrinsic component of external side of plasma membrane
GO:0034185 apolipoprotein binding
GO:0042730 fibrinolysis
GO:0044267 cellular protein metabolic process
GO:0048771 tissue remodeling
GO:0051918 negative regulation of fibrinolysis
GO:0051919 positive regulation of fibrinolysis
GO:0002576 platelet degranulation
GO:0004252 serine-type endopeptidase activity
GO:0006508 proteolysis
GO:0007596 blood coagulation
GO:0009986 cell surface
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000001 KringleDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR003609 PAN/Apple domainDomainDomain
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR018056 Kringle, conserved siteSiteConserved site
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR023317 Peptidase S1A, plasminFamilyFamily
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR038178 Kringle superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00009 AlteplaseDrugbankbiotech
DB00013 UrokinaseDrugbankbiotech
DB00015 ReteplaseDrugbankbiotech
DB00029 AnistreplaseDrugbankbiotech
DB00031 TenecteplaseDrugbankbiotech
DB00086 StreptokinaseDrugbankbiotech
DB00302 Tranexamic acidDrugbanksmall molecule
DB00513 Aminocaproic acidDrugbanksmall molecule
DB03709 BicineDrugbanksmall molecule
DB04925 DesmoteplaseDrugbankbiotech
DB06692 AprotininDrugbankbiotech
DB09130 CopperDrugbanksmall molecule
DB12831 GabexateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PLMN_HUMANPLRKT_MOUSEUniProt19897580 details