Entity Details

Primary name ANT3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01008
EntryNameANT3_HUMAN
FullNameAntithrombin-III
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesSERPINC1

GO terms

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GOName
GO:0002020 protease binding
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0007584 response to nutrient
GO:0007595 lactation
GO:0007596 blood coagulation
GO:0008201 heparin binding
GO:0010951 negative regulation of endopeptidase activity
GO:0042802 identical protein binding
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:2000266 regulation of blood coagulation, intrinsic pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR015555 Antithrombin-IIIFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR033829 Antithrombin-III, serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00407 ArdeparinDrugbanksmall molecule
DB00569 FondaparinuxDrugbanksmall molecule
DB01109 HeparinDrugbanksmall molecule
DB01225 EnoxaparinDrugbanksmall molecule
DB04464 N-FormylmethionineDrugbanksmall molecule
DB05361 SR-123781ADrugbanksmall molecule
DB06271 SulodexideDrugbankbiotech
DB06754 DanaparoidDrugbanksmall molecule
DB06779 DalteparinDrugbanksmall molecule
DB06822 TinzaparinDrugbanksmall molecule
DB08813 NadroparinDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB09141 Protamine sulfateDrugbankbiotech
DB09258 BemiparinDrugbanksmall molecule
DB11598 Antithrombin III humanDrugbankbiotech

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink