Entity Details

Primary name AACT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01011
EntryNameAACT_HUMAN
FullNameAlpha-1-antichymotrypsin
TaxID9606
Evidenceevidence at protein level
Length423
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesSERPINA3

GO terms

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GOName
GO:0002576 platelet degranulation
GO:0003677 DNA binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0006953 acute-phase response
GO:0006954 inflammatory response
GO:0010951 negative regulation of endopeptidase activity
GO:0019216 regulation of lipid metabolic process
GO:0030277 maintenance of gastrointestinal epithelium
GO:0031093 platelet alpha granule lumen
GO:0034774 secretory granule lumen
GO:0035578 azurophil granule lumen
GO:0043312 neutrophil degranulation
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink