Entity Details

Primary name SOMA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01241
EntryNameSOMA_HUMAN
FullNameSomatotropin
TaxID9606
Evidenceevidence at protein level
Length217
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesGH1

GO terms

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GOName
GO:0005131 growth hormone receptor binding
GO:0005148 prolactin receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0008083 growth factor activity
GO:0010536 positive regulation of activation of Janus kinase activity
GO:0010828 positive regulation of glucose transmembrane transport
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0031667 response to nutrient levels
GO:0031904 endosome lumen
GO:0032355 response to estradiol
GO:0040018 positive regulation of multicellular organism growth
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043406 positive regulation of MAP kinase activity
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045927 positive regulation of growth
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046872 metal ion binding
GO:0048513 animal organ development
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0060396 growth hormone receptor signaling pathway
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT
GO:0070195 growth hormone receptor complex
GO:0070977 bone maturation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001400 Somatotropin/prolactinFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR018116 Somatotropin hormone, conserved siteSiteConserved site

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink