Entity Details

Primary name KAPCA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP05132
EntryNameKAPCA_MOUSE
FullNamecAMP-dependent protein kinase catalytic subunit alpha
TaxID10090
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesPrkaca

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001669 acrosomal vesicle
GO:0001707 mesoderm formation
GO:0001843 neural tube closure
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004679 AMP-activated protein kinase activity
GO:0004691 cAMP-dependent protein kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005930 axoneme
GO:0005952 cAMP-dependent protein kinase complex
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
GO:0008284 positive regulation of cell population proliferation
GO:0010737 protein kinase A signaling
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0030145 manganese ion binding
GO:0031267 small GTPase binding
GO:0031588 nucleotide-activated protein kinase complex
GO:0031594 neuromuscular junction
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0034237 protein kinase A regulatory subunit binding
GO:0034605 cellular response to heat
GO:0036126 sperm flagellum
GO:0043005 neuron projection
GO:0043197 dendritic spine
GO:0043457 regulation of cellular respiration
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045667 regulation of osteoblast differentiation
GO:0046777 protein autophosphorylation
GO:0046827 positive regulation of protein export from nucleus
GO:0048240 sperm capacitation
GO:0048471 perinuclear region of cytoplasm
GO:0048792 spontaneous exocytosis of neurotransmitter
GO:0050804 modulation of chemical synaptic transmission
GO:0051447 negative regulation of meiotic cell cycle
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0061136 regulation of proteasomal protein catabolic process
GO:0070613 regulation of protein processing
GO:0071333 cellular response to glucose stimulus
GO:0071374 cellular response to parathyroid hormone stimulus
GO:0097225 sperm midpiece
GO:0097546 ciliary base
GO:0098793 presynapse
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Membrane
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR044109 cAMP-dependent protein kinase catalytic subunitFamilyFamily

Diseases

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