Entity Details

Primary name SCN1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2APX8
EntryNameSCN1A_MOUSE
FullNameSodium channel protein type 1 subunit alpha
TaxID10090
Evidenceevidence at protein level
Length2009
SequenceStatuscomplete
DateCreated2016-10-05
DateModified2021-06-02

Ontological Relatives

GenesScn1a

GO terms

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GOName
GO:0001508 action potential
GO:0001518 voltage-gated sodium channel complex
GO:0005244 voltage-gated ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0006814 sodium ion transport
GO:0007628 adult walking behavior
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016604 nuclear body
GO:0019227 neuronal action potential propagation
GO:0019228 neuronal action potential
GO:0030018 Z disc
GO:0030315 T-tubule
GO:0030424 axon
GO:0031402 sodium ion binding
GO:0033268 node of Ranvier
GO:0034706 sodium channel complex
GO:0034765 regulation of ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043025 neuronal cell body
GO:0043194 axon initial segment
GO:0050884 neuromuscular process controlling posture
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086010 membrane depolarization during action potential
GO:0099056 integral component of presynaptic membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001696 Voltage gated sodium channel, alpha subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR008051 Voltage gated sodium channel, alpha-1 subunitFamilyFamily
IPR010526 Sodium ion transport-associatedDomainDomain
IPR024583 Voltage-gated Na+ ion channel, cytoplasmic domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR043203 Voltage-gated cation channel calcium and sodiumFamilyFamily
IPR044564 Voltage-gated sodium channel alpha subunit, inactivation gateDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SCN1A_MOUSENEDD4_MOUSEBioGRID15123669 details