Entity Details

Primary name DQB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01920
EntryNameDQB1_HUMAN
FullNameHLA class II histocompatibility antigen, DQ beta 1 chain
TaxID9606
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesHLA-DQB1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002250 adaptive immune response
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0006959 humoral immune response
GO:0010008 endosome membrane
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 transport vesicle membrane
GO:0030666 endocytic vesicle membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0032395 MHC class II receptor activity
GO:0032588 trans-Golgi network membrane
GO:0042605 peptide antigen binding
GO:0042613 MHC class II protein complex
GO:0050852 T cell receptor signaling pathway
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane
Endosome membrane
Golgi apparatus
Lysosome membrane

Domains

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DomainNameCategoryType
IPR000353 MHC class II, beta chain, N-terminalDomainDomain
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014745 MHC class II, alpha/beta chain, N-terminalFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00071 Insulin porkDrugbankbiotech

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink