Entity Details

Primary name CRYAB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02511
EntryNameCRYAB_HUMAN
FullNameAlpha-crystallin B chain
TaxID9606
Evidenceevidence at protein level
Length175
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCRYAB

GO terms

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GOName
GO:0007021 tubulin complex assembly
GO:0010629 negative regulation of gene expression
GO:0014069 postsynaptic density
GO:0030018 Z disc
GO:0030424 axon
GO:0042542 response to hydrogen peroxide
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0070062 extracellular exosome
GO:0005198 structural molecule activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006457 protein folding
GO:0006936 muscle contraction
GO:0007517 muscle organ development
GO:0009986 cell surface
GO:0010941 regulation of cell death
GO:0015630 microtubule cytoskeleton
GO:0032355 response to estradiol
GO:0032432 actin filament bundle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051403 stress-activated MAPK cascade
GO:0060561 apoptotic process involved in morphogenesis
GO:0071480 cellular response to gamma radiation
GO:1905907 negative regulation of amyloid fibril formation
GO:0005829 cytosol
GO:0008017 microtubule binding
GO:0010259 multicellular organism aging
GO:0030308 negative regulation of cell growth
GO:0031109 microtubule polymerization or depolymerization
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046872 metal ion binding
GO:0097060 synaptic membrane
GO:0097512 cardiac myofibril
GO:0001540 amyloid-beta binding
GO:0001666 response to hypoxia
GO:0002088 lens development in camera-type eye
GO:0005212 structural constituent of eye lens
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031430 M band
GO:0032387 negative regulation of intracellular transport
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:1900034 regulation of cellular response to heat
GO:2000378 negative regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus
Secreted
Cytoplasm

Domains

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DomainNameCategoryType
IPR001436 Alpha crystallin/Small heat shock protein, animal typeFamilyFamily
IPR002068 Alpha crystallin/Hsp20 domainDomainDomain
IPR003090 Alpha-crystallin, N-terminalDomainDomain
IPR008978 HSP20-like chaperoneFamilyHomologous superfamily
IPR037882 Alpha-crystallin B chain, ACD domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CRYAB_HUMANTM109_MOUSEMINT23542032 details