Entity Details

Primary name SPTA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02549
EntryNameSPTA1_HUMAN
FullNameSpectrin alpha chain, erythrocytic 1
TaxID9606
Evidenceevidence at protein level
Length2419
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesSPTA1

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002260 lymphocyte homeostasis
GO:0005200 structural constituent of cytoskeleton
GO:0005509 calcium ion binding
GO:0005829 cytosol
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007009 plasma membrane organization
GO:0007015 actin filament organization
GO:0007411 axon guidance
GO:0008091 spectrin
GO:0008360 regulation of cell shape
GO:0014731 spectrin-associated cytoskeleton
GO:0015629 actin cytoskeleton
GO:0030097 hemopoiesis
GO:0030424 axon
GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032092 positive regulation of protein binding
GO:0032437 cuticular plate
GO:0042102 positive regulation of T cell proliferation
GO:0051015 actin filament binding
GO:0051693 actin filament capping

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR014837 EF-hand, Ca insensitiveDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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