Entity Details

Primary name CRP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02741
EntryNameCRP_HUMAN
FullNameC-reactive protein
TaxID9606
Evidenceevidence at protein level
Length224
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCRP

GO terms

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GOName
GO:0001849 complement component C1q complex binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006953 acute-phase response
GO:0006954 inflammatory response
GO:0006958 complement activation, classical pathway
GO:0008228 opsonization
GO:0010628 positive regulation of gene expression
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0030169 low-density lipoprotein particle binding
GO:0032677 regulation of interleukin-8 production
GO:0032930 positive regulation of superoxide anion generation
GO:0032945 negative regulation of mononuclear cell proliferation
GO:0033265 choline binding
GO:0042310 vasoconstriction
GO:0042802 identical protein binding
GO:0044793 negative regulation by host of viral process
GO:0045087 innate immune response
GO:0050750 low-density lipoprotein particle receptor binding
GO:0050830 defense response to Gram-positive bacterium

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001759 Pentraxin-relatedFamilyFamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR030476 Pentaxin, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB03945 N,N,N-Trimethyl-2-(phosphonooxy)ethanaminiumDrugbanksmall molecule
DB05744 CRx-139Drugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink