Entity Details

Primary name C1QA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02745
EntryNameC1QA_HUMAN
FullNameComplement C1q subcomponent subunit A
TaxID9606
Evidenceevidence at protein level
Length245
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesC1QA

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005602 complement component C1 complex
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0007267 cell-cell signaling
GO:0007568 aging
GO:0010039 response to iron ion
GO:0016032 viral process
GO:0016322 neuron remodeling
GO:0030449 regulation of complement activation
GO:0045087 innate immune response
GO:0045202 synapse
GO:0048143 astrocyte activation
GO:0050808 synapse organization
GO:0062023 collagen-containing extracellular matrix
GO:0098794 postsynapse
GO:0098883 synapse pruning
GO:0150062 complement-mediated synapse pruning
GO:0150064 vertebrate eye-specific patterning
GO:1901216 positive regulation of neuron death

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001073 C1q domainDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily
IPR037572 Complement C1q subcomponent subunit AFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00002 CetuximabDrugbankbiotech
DB00005 EtanerceptDrugbankbiotech
DB00110 PalivizumabDrugbankbiotech
DB00111 DaclizumabDrugbankbiotech
DB00112 BevacizumabDrugbankbiotech

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink