Entity Details

Primary name FRIH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02794
EntryNameFRIH_HUMAN
FullNameFerritin heavy chain
TaxID9606
Evidenceevidence at protein level
Length183
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesFTH1

GO terms

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GOName
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006955 immune response
GO:0008043 intracellular ferritin complex
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0008285 negative regulation of cell population proliferation
GO:0043312 neutrophil degranulation
GO:0044754 autolysosome
GO:0048147 negative regulation of fibroblast proliferation
GO:0070062 extracellular exosome
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001519 FerritinFamilyFamily
IPR008331 Ferritin/DPS protein domainDomainDomain
IPR009040 Ferritin-like diiron domainDomainDomain
IPR009078 Ferritin-like superfamilyFamilyHomologous superfamily
IPR012347 Ferritin-likeFamilyHomologous superfamily
IPR014034 Ferritin, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00893 Iron DextranDrugbanksmall molecule
DB01592 IronDrugbanksmall molecule
DB06215 FerumoxytolSwissprotsmall molecule
DB06784 Gallium citrate Ga-67Swissprotsmall molecule
DB13995 Ferric pyrophosphate citrateDrugbanksmall molecule
DB14488 Ferrous gluconateDrugbanksmall molecule
DB14489 Ferrous succinateDrugbanksmall molecule
DB14490 Ferrous ascorbateDrugbanksmall molecule
DB14491 Ferrous fumarateDrugbanksmall molecule
DB14501 Ferrous glycine sulfateDrugbanksmall molecule

Interactions

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