Entity Details

Primary name KIT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP05532
EntryNameKIT_MOUSE
FullNameMast/stem cell growth factor receptor Kit
TaxID10090
Evidenceevidence at protein level
Length979
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesKit

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001541 ovarian follicle development
GO:0001650 fibrillar center
GO:0001669 acrosomal vesicle
GO:0002020 protease binding
GO:0002244 hematopoietic progenitor cell differentiation
GO:0002318 myeloid progenitor cell differentiation
GO:0002320 lymphoid progenitor cell differentiation
GO:0002327 immature B cell differentiation
GO:0002551 mast cell chemotaxis
GO:0002573 myeloid leukocyte differentiation
GO:0002732 positive regulation of dendritic cell cytokine production
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005020 stem cell factor receptor activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0006687 glycosphingolipid metabolic process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007281 germ cell development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008284 positive regulation of cell population proliferation
GO:0008354 germ cell migration
GO:0008360 regulation of cell shape
GO:0008542 visual learning
GO:0008584 male gonad development
GO:0009314 response to radiation
GO:0009897 external side of plasma membrane
GO:0009898 cytoplasmic side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0030032 lamellipodium assembly
GO:0030097 hemopoiesis
GO:0030154 cell differentiation
GO:0030183 B cell differentiation
GO:0030217 T cell differentiation
GO:0030218 erythrocyte differentiation
GO:0030318 melanocyte differentiation
GO:0030335 positive regulation of cell migration
GO:0031274 positive regulation of pseudopodium assembly
GO:0031532 actin cytoskeleton reorganization
GO:0032765 positive regulation of mast cell cytokine production
GO:0033674 positive regulation of kinase activity
GO:0035019 somatic stem cell population maintenance
GO:0035162 embryonic hemopoiesis
GO:0035234 ectopic germ cell programmed cell death
GO:0035556 intracellular signal transduction
GO:0035701 hematopoietic stem cell migration
GO:0035855 megakaryocyte development
GO:0038093 Fc receptor signaling pathway
GO:0038109 Kit signaling pathway
GO:0038162 erythropoietin-mediated signaling pathway
GO:0042169 SH2 domain binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042803 protein homodimerization activity
GO:0043069 negative regulation of programmed cell death
GO:0043235 receptor complex
GO:0043303 mast cell degranulation
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043473 pigmentation
GO:0043586 tongue development
GO:0045747 positive regulation of Notch signaling pathway
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046686 response to cadmium ion
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048066 developmental pigmentation
GO:0048103 somatic stem cell division
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048565 digestive tract development
GO:0048863 stem cell differentiation
GO:0050673 epithelial cell proliferation
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060326 cell chemotaxis
GO:0060374 mast cell differentiation
GO:0097067 cellular response to thyroid hormone stimulus
GO:0097324 melanocyte migration
GO:0097326 melanocyte adhesion
GO:0120072 positive regulation of pyloric antrum smooth muscle contraction
GO:1904251 regulation of bile acid metabolic process
GO:1904343 positive regulation of colon smooth muscle contraction
GO:1904349 positive regulation of small intestine smooth muscle contraction
GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001824 Tyrosine-protein kinase, receptor class III, conserved siteSiteConserved site
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR027263 Mast/stem cell growth factor receptorFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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