Entity Details

Primary name ALDOA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04075
EntryNameALDOA_HUMAN
FullNameFructose-bisphosphate aldolase A
TaxID9606
Evidenceevidence at protein level
Length364
SequenceStatuscomplete
DateCreated1986-11-01
DateModified2021-06-02

Ontological Relatives

GenesALDOA

GO terms

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GOName
GO:0002576 platelet degranulation
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0004332 fructose-bisphosphate aldolase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0006754 ATP biosynthetic process
GO:0006941 striated muscle contraction
GO:0007015 actin filament organization
GO:0007339 binding of sperm to zona pellucida
GO:0008092 cytoskeletal protein binding
GO:0008360 regulation of cell shape
GO:0015629 actin cytoskeleton
GO:0015631 tubulin binding
GO:0016020 membrane
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0031093 platelet alpha granule lumen
GO:0031430 M band
GO:0031674 I band
GO:0034774 secretory granule lumen
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0045296 cadherin binding
GO:0046716 muscle cell cellular homeostasis
GO:0051289 protein homotetramerization
GO:0061621 canonical glycolysis
GO:0061827 sperm head
GO:0070061 fructose binding
GO:0070062 extracellular exosome
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000741 Fructose-bisphosphate aldolase, class-IFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR029768 Fructose-bisphosphate aldolase class-I active siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB02512 1,6-Fructose Diphosphate (Linear Form)Drugbanksmall molecule
DB04326 Dihydroxyacetone phosphateDrugbanksmall molecule
DB04733 1,6-DI-O-PHOSPHONO-D-MANNITOLDrugbanksmall molecule
DB08240 N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDEDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ALDOA_HUMANMK13_MOUSEBioGRID19135240 details