Entity Details

Primary name MYCN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04198
EntryNameMYCN_HUMAN
FullNameN-myc proto-oncogene protein
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1987-03-20
DateModified2021-06-02

Ontological Relatives

GenesMYCN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0019900 kinase binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002418 Transcription regulator MycFamilyFamily
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR012682 Transcription regulator Myc, N-terminalDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MYCN_HUMANAURKA_MOUSEIntAct23792191 25533335 details