Entity Details

Primary name G3P_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04406
EntryNameG3P_HUMAN
FullNameGlyceraldehyde-3-phosphate dehydrogenase
TaxID9606
Evidenceevidence at protein level
Length335
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesGAPDH

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0001819 positive regulation of cytokine production
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0008017 microtubule binding
GO:0010951 negative regulation of endopeptidase activity
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016241 regulation of macroautophagy
GO:0017148 negative regulation of translation
GO:0019828 aspartic-type endopeptidase inhibitor activity
GO:0031640 killing of cells of other organism
GO:0031965 nuclear membrane
GO:0031982 vesicle
GO:0035605 peptidyl-cysteine S-nitrosylase activity
GO:0035606 peptidyl-cysteine S-trans-nitrosylation
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0050661 NADP binding
GO:0050821 protein stabilization
GO:0050832 defense response to fungus
GO:0051287 NAD binding
GO:0051402 neuron apoptotic process
GO:0051873 killing by host of symbiont cells
GO:0061621 canonical glycolysis
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070062 extracellular exosome
GO:0071346 cellular response to interferon-gamma
GO:0097452 GAIT complex
GO:0097718 disordered domain specific binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type IFamilyFamily
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domainDomainDomain
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domainDomainDomain
IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active siteSiteActive site
IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase familyFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB02059 Adenosine-5-DiphosphoriboseDrugbanksmall molecule
DB03893 Thionicotinamide-Adenine-DinucleotideDrugbanksmall molecule
DB07347 4-(2-Aminoethyl)Benzenesulfonyl FluorideDrugbanksmall molecule
DB09092 XanthinolDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
G3P_HUMANAKT2_MOUSEIntAct23823123 details
G3P_HUMANMK13_MOUSEBioGRID19135240 details