Entity Details

Primary name HSPB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04792
EntryNameHSPB1_HUMAN
FullNameHeat shock protein beta-1
TaxID9606
Evidenceevidence at protein level
Length205
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesHSPB1

GO terms

Show/Hide Table
GOName
GO:0000502 proteasome complex
GO:0001895 retina homeostasis
GO:0001932 regulation of protein phosphorylation
GO:0003723 RNA binding
GO:0005080 protein kinase C binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
GO:0006446 regulation of translational initiation
GO:0006469 negative regulation of protein kinase activity
GO:0006986 response to unfolded protein
GO:0008426 protein kinase C inhibitor activity
GO:0009615 response to virus
GO:0010506 regulation of autophagy
GO:0016032 viral process
GO:0019901 protein kinase binding
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035556 intracellular signal transduction
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0043488 regulation of mRNA stability
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0044183 protein folding chaperone
GO:0045766 positive regulation of angiogenesis
GO:0061077 chaperone-mediated protein folding
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
GO:0070062 extracellular exosome
GO:0070527 platelet aggregation
GO:0099641 anterograde axonal protein transport
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1904115 axon cytoplasm
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001436 Alpha crystallin/Small heat shock protein, animal typeFamilyFamily
IPR002068 Alpha crystallin/Hsp20 domainDomainDomain
IPR008978 HSP20-like chaperoneFamilyHomologous superfamily
IPR037876 Heat shock protein beta-1, ACD domainDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB06094 ApatorsenDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HSPB1_HUMANMAPK5_MOUSEIntAct17254968 details