Entity Details

Primary name K1C18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05783
EntryNameK1C18_HUMAN
FullNameKeratin, type I cytoskeletal 18
TaxID9606
Evidenceevidence at protein level
Length430
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesKRT18

GO terms

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GOName
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0005912 adherens junction
GO:0007049 cell cycle
GO:0009653 anatomical structure morphogenesis
GO:0009750 response to fructose
GO:0009897 external side of plasma membrane
GO:0016032 viral process
GO:0031424 keratinization
GO:0031667 response to nutrient levels
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034451 centriolar satellite
GO:0043000 Golgi to plasma membrane CFTR protein transport
GO:0043066 negative regulation of apoptotic process
GO:0045095 keratin filament
GO:0045104 intermediate filament cytoskeleton organization
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome
GO:0070268 cornification
GO:0070365 hepatocyte differentiation
GO:0072497 mesenchymal stem cell differentiation
GO:0097110 scaffold protein binding
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097284 hepatocyte apoptotic process
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:1902488 cholangiocyte apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002957 Keratin, type IFamilyFamily
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR027695 Keratin, type I cytoskeletal 18FamilyFamily
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
K1C18_HUMAN1433Z_MOUSEMINT9524113 details