Entity Details

Primary name K2C8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05787
EntryNameK2C8_HUMAN
FullNameKeratin, type II cytoskeletal 8
TaxID9606
Evidenceevidence at protein level
Length483
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesKRT8

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0005911 cell-cell junction
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016032 viral process
GO:0016327 apicolateral plasma membrane
GO:0016363 nuclear matrix
GO:0030018 Z disc
GO:0031424 keratinization
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042383 sarcolemma
GO:0043034 costamere
GO:0044877 protein-containing complex binding
GO:0045095 keratin filament
GO:0045111 intermediate filament cytoskeleton
GO:0045214 sarcomere organization
GO:0051599 response to hydrostatic pressure
GO:0051707 response to other organism
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0070062 extracellular exosome
GO:0070268 cornification
GO:0097110 scaffold protein binding
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097284 hepatocyte apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR003054 Keratin, type IIFamilyFamily
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR032444 Keratin type II headDomainDomain
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00031 TenecteplaseDrugbankbiotech
DB06245 LanoteplaseDrugbankbiotech
DB09130 CopperDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink