Entity Details

Primary name ENOA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06733
EntryNameENOA_HUMAN
FullNameAlpha-enolase
TaxID9606
Evidenceevidence at protein level
Length434
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesENO1

GO terms

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GOName
GO:0000015 phosphopyruvate hydratase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000287 magnesium ion binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003723 RNA binding
GO:0004634 phosphopyruvate hydratase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0009615 response to virus
GO:0009986 cell surface
GO:0010756 positive regulation of plasminogen activation
GO:0016020 membrane
GO:0030308 negative regulation of cell growth
GO:0031430 M band
GO:0032889 regulation of vacuole fusion, non-autophagic
GO:0042803 protein homodimerization activity
GO:0044003 modulation by symbiont of host process
GO:0045296 cadherin binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045933 positive regulation of muscle contraction
GO:0051020 GTPase binding
GO:0061621 canonical glycolysis
GO:0070062 extracellular exosome
GO:0099738 cell cortex region
GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
GO:2001171 positive regulation of ATP biosynthetic process

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000941 EnolaseFamilyFamily
IPR020809 Enolase, conserved siteSiteConserved site
IPR020810 Enolase, C-terminal TIM barrel domainDomainDomain
IPR020811 Enolase, N-terminalDomainDomain
IPR029017 Enolase-like, N-terminalFamilyHomologous superfamily
IPR036849 Enolase-like, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ENOA_HUMANAKT2_MOUSEIntAct23823123 details
ENOA_HUMANMK13_MOUSEBioGRID19135240 details