Entity Details

Primary name G6PI_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06744
EntryNameG6PI_HUMAN
FullNameGlucose-6-phosphate isomerase
TaxID9606
Evidenceevidence at protein level
Length558
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesGPI

GO terms

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GOName
GO:0002639 positive regulation of immunoglobulin production
GO:0004347 glucose-6-phosphate isomerase activity
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005975 carbohydrate metabolic process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0006959 humoral immune response
GO:0007599 hemostasis
GO:0008083 growth factor activity
GO:0010595 positive regulation of endothelial cell migration
GO:0016020 membrane
GO:0031625 ubiquitin protein ligase binding
GO:0034774 secretory granule lumen
GO:0043312 neutrophil degranulation
GO:0048029 monosaccharide binding
GO:0051156 glucose 6-phosphate metabolic process
GO:0061621 canonical glycolysis
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001672 Phosphoglucose isomerase (PGI)FamilyFamily
IPR018189 Phosphoglucose isomerase, conserved siteSiteConserved site
IPR023096 Phosphoglucose isomerase, C-terminalFamilyHomologous superfamily
IPR035476 Phosphoglucose isomerase, SIS domain 1DomainDomain
IPR035482 Phosphoglucose isomerase, SIS domain 2DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02007 alpha-D-glucose 6-phosphateDrugbanksmall molecule
DB02076 6-phospho-D-gluconic acidDrugbanksmall molecule
DB02093 5-phospho-D-arabinohydroxamic acidDrugbanksmall molecule
DB02548 D-glucitol 6-phosphateDrugbanksmall molecule
DB03042 5-Phosphoarabinonic AcidDrugbanksmall molecule
DB03581 Glucose-6-PhosphateDrugbanksmall molecule
DB03937 D-erythrose 4-phosphateDrugbanksmall molecule
DB04493 Fructose-6-phosphateDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink