Entity Details

Primary name ANXA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07355
EntryNameANXA2_HUMAN
FullNameAnnexin A2
TaxID9606
Evidenceevidence at protein level
Length339
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesANXA2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001765 membrane raft assembly
GO:0001786 phosphatidylserine binding
GO:0001921 positive regulation of receptor recycling
GO:0002020 protease binding
GO:0003723 RNA binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005811 lipid droplet
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0006900 vesicle budding from membrane
GO:0008092 cytoskeletal protein binding
GO:0009986 cell surface
GO:0016020 membrane
GO:0016032 viral process
GO:0016323 basolateral plasma membrane
GO:0019834 phospholipase A2 inhibitor activity
GO:0030496 midbody
GO:0031340 positive regulation of vesicle fusion
GO:0031902 late endosome membrane
GO:0031982 vesicle
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process
GO:0035578 azurophil granule lumen
GO:0035722 interleukin-12-mediated signaling pathway
GO:0036035 osteoclast development
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0044090 positive regulation of vacuole organization
GO:0044147 negative regulation of formation of structure involved in a symbiotic process
GO:0044548 S100 protein binding
GO:0046790 virion binding
GO:0048306 calcium-dependent protein binding
GO:0052362 obsolete catabolism by host of symbiont protein
GO:0052405 negative regulation by host of symbiont molecular function
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:1905581 positive regulation of low-density lipoprotein particle clearance
GO:1905597 positive regulation of low-density lipoprotein particle receptor binding
GO:1905599 positive regulation of low-density lipoprotein receptor activity
GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport
GO:1990665 AnxA2-p11 complex
GO:1990667 PCSK9-AnxA2 complex

Subcellular Location

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Subcellular Location
Melanosome
Secreted

Domains

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DomainNameCategoryType
IPR001464 AnnexinFamilyFamily
IPR002389 Annexin A2FamilyFamily
IPR018252 Annexin repeat, conserved siteSiteConserved site
IPR018502 Annexin repeatRepeatRepeat
IPR037104 Annexin superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00031 TenecteplaseDrugbankbiotech
DB00591 Fluocinolone acetonideDrugbanksmall molecule
DB06245 LanoteplaseDrugbankbiotech
DB11638 ArtenimolDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ANXA2_HUMANKSR1_MOUSEBioGRID10409742 details