Entity Details

Primary name SP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08047
EntryNameSP1_HUMAN
FullNameTranscription factor Sp1
TaxID9606
Evidenceevidence at protein level
Length785
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesSP1

GO terms

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GOName
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0017053 transcription repressor complex
GO:0019216 regulation of lipid metabolic process
GO:0032869 cellular response to insulin stimulus
GO:0032993 protein-DNA complex
GO:0033194 response to hydroperoxide
GO:0035035 histone acetyltransferase binding
GO:0042795 snRNA transcription by RNA polymerase II
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043425 bHLH transcription factor binding
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043565 sequence-specific DNA binding
GO:0043923 positive regulation by host of viral transcription
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048511 rhythmic process
GO:0071837 HMG box domain binding
GO:1902004 positive regulation of amyloid-beta formation
GO:1904828 positive regulation of hydrogen sulfide biosynthetic process
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SP1_HUMANNFYA_MOUSEMINT10393239 details