Entity Details

Primary name CO5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP06684
EntryNameCO5_MOUSE
FullNameComplement C5
TaxID10090
Evidenceevidence at protein level
Length1680
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesHc

GO terms

Show/Hide Table
GOName
GO:0001701 in utero embryonic development
GO:0004866 endopeptidase inhibitor activity
GO:0005579 membrane attack complex
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010760 negative regulation of macrophage chemotaxis
GO:0019835 cytolysis
GO:0032722 positive regulation of chemokine production
GO:0045766 positive regulation of angiogenesis

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000020 Anaphylatoxin/fibulinDomainDomain
IPR001134 Netrin domainDomainDomain
IPR001599 Alpha-2-macroglobulinDomainDomain
IPR002890 Macroglobulin domainDomainDomain
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidFamilyHomologous superfamily
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-foldFamilyHomologous superfamily
IPR009048 Alpha-macroglobulin, receptor-bindingDomainDomain
IPR011625 Alpha-2-macroglobulin, bait region domainDomainDomain
IPR011626 Alpha-macroglobulin-like, TED domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR018081 Anaphylatoxin, complement systemFamilyHomologous superfamily
IPR018933 Netrin module, non-TIMP typeDomainDomain
IPR036595 Alpha-macroglobulin, receptor-binding domain superfamilyFamilyHomologous superfamily
IPR037562 Complement C5FamilyFamily
IPR040839 Macroglobulin domain MG4DomainDomain
IPR041425 Complement C3/4/5, macroglobulin domain MG1DomainDomain
IPR041555 Macroglobulin domain MG3DomainDomain

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CO5_MOUSEC5AR1_MOUSEInnateDB23263555 details
CO5_MOUSEC5AR2_MOUSEInnateDB23263555 details