Entity Details

Primary name RU17_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08621
EntryNameRU17_HUMAN
FullNameU1 small nuclear ribonucleoprotein 70 kDa
TaxID9606
Evidenceevidence at protein level
Length437
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesSNRNP70

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0016607 nuclear speck
GO:0017069 snRNA binding
GO:0030619 U1 snRNA binding
GO:0043462 regulation of ATPase activity
GO:0043484 regulation of RNA splicing
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0061084 negative regulation of protein refolding
GO:0071004 U2-type prespliceosome
GO:1904715 negative regulation of chaperone-mediated autophagy

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR022023 U1 small nuclear ribonucleoprotein of 70kDa N-terminalDomainDomain
IPR034143 snRNP70, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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