Entity Details

Primary name MDR1B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP06795
EntryNameMDR1B_MOUSE
FullNameATP-dependent translocase ABCB1
TaxID10090
Evidenceevidence at protein level
Length1276
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesAbcb1b

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0008559 ABC-type xenobiotic transporter activity
GO:0014045 establishment of endothelial blood-brain barrier
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0042493 response to drug
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042910 xenobiotic transmembrane transporter activity
GO:0045332 phospholipid translocation
GO:0046581 intercellular canaliculus
GO:0061843 Sertoli cell barrier remodeling
GO:0090554 phosphatidylcholine floppase activity
GO:0090555 phosphatidylethanolamine flippase activity
GO:0098591 external side of apical plasma membrane
GO:0099038 ceramide floppase activity
GO:0099040 ceramide translocation
GO:0140328 floppase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily
IPR039421 Type 1 protein exporterFamilyFamily

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink