Entity Details

Primary name ENPP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP06802
EntryNameENPP1_MOUSE
FullNameEctonucleotide pyrophosphatase/phosphodiesterase family member 1
TaxID10090
Evidenceevidence at protein level
Length906
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesEnpp1

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004528 phosphodiesterase I activity
GO:0004551 nucleotide diphosphatase activity
GO:0005044 scavenger receptor activity
GO:0005158 insulin receptor binding
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0006796 phosphate-containing compound metabolic process
GO:0006955 immune response
GO:0008270 zinc ion binding
GO:0009143 nucleoside triphosphate catabolic process
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0030247 polysaccharide binding
GO:0030279 negative regulation of ossification
GO:0030308 negative regulation of cell growth
GO:0030318 melanocyte differentiation
GO:0030500 regulation of bone mineralization
GO:0030502 negative regulation of bone mineralization
GO:0030505 inorganic diphosphate transport
GO:0030643 cellular phosphate ion homeostasis
GO:0030730 sequestering of triglyceride
GO:0031214 biomineral tissue development
GO:0031953 negative regulation of protein autophosphorylation
GO:0032869 cellular response to insulin stimulus
GO:0035529 NADH pyrophosphatase activity
GO:0036218 dTTP diphosphatase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042995 cell projection
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044297 cell body
GO:0045202 synapse
GO:0045599 negative regulation of fat cell differentiation
GO:0045719 negative regulation of glycogen biosynthetic process
GO:0046034 ATP metabolic process
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046849 bone remodeling
GO:0047429 nucleoside-triphosphate diphosphatase activity
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0097440 apical dendrite
GO:0097441 basal dendrite
GO:0106177 cyclic-GMP-AMP hydrolase activity
GO:1990787 negative regulation of hh target transcription factor activity

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR001212 Somatomedin B domainDomainDomain
IPR001604 DNA/RNA non-specific endonucleaseDomainDomain
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferaseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR020436 Somatomedin B, chordataDomainDomain
IPR020821 Extracellular Endonuclease, subunit ADomainDomain
IPR029890 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1FamilyFamily
IPR036024 Somatomedin B-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ENPP1_MOUSEENPP1_MOUSEDIP23041369 details