Entity Details

Primary name UBC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP0CG48
EntryNameUBC_HUMAN
FullNamePolyubiquitin-C
TaxID9606
Evidenceevidence at protein level
Length685
SequenceStatuscomplete
DateCreated2010-08-10
DateModified2021-06-02

Ontological Relatives

GenesUBC

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0005634 nucleus
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0008104 protein localization
GO:0016197 endosomal transport
GO:0016567 protein ubiquitination
GO:0019985 translesion synthesis
GO:0030666 endocytic vesicle membrane
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031386 protein tag
GO:0031982 vesicle
GO:0033683 nucleotide-excision repair, DNA incision
GO:0042276 error-prone translesion synthesis
GO:0043065 positive regulation of apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0052031 modulation by symbiont of host defense response
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070987 error-free translesion synthesis
GO:0002020 protease binding
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0019068 virion assembly
GO:0019081 viral translation
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0035973 aggrephagy
GO:0036297 interstrand cross-link repair
GO:0042769 DNA damage response, detection of DNA damage
GO:0043488 regulation of mRNA stability
GO:0043657 host cell
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0005615 extracellular space
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0007096 regulation of exit from mitosis
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0010008 endosome membrane
GO:0019058 viral life cycle
GO:0019221 cytokine-mediated signaling pathway
GO:0019941 modification-dependent protein catabolic process
GO:0036388 pre-replicative complex assembly
GO:0043066 negative regulation of apoptotic process
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070911 global genome nucleotide-excision repair
GO:0075733 intracellular transport of virus
GO:1904380 endoplasmic reticulum mannose trimming
GO:1990000 amyloid fibril formation
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000187 obsolete activation of MAPK activity
GO:0002753 cytoplasmic pattern recognition receptor signaling pathway
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0016055 Wnt signaling pathway
GO:0016579 protein deubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0044322 endoplasmic reticulum quality control compartment
GO:0051403 stress-activated MAPK cascade
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Nucleus
Cytoplasm

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR019954 Ubiquitin conserved siteSiteConserved site
IPR019956 Ubiquitin domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04464 N-FormylmethionineDrugbanksmall molecule

Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
UBC_HUMANEPS15_MOUSEMINT12750381 details
UBC_HUMANHDAC6_MOUSEMINT11689694 details
UBC_HUMANNBR1_MOUSEMINT19427866 details
UBC_HUMANPOLI_MOUSEBioGRID16357261 details
UBC_HUMANRYBP_MOUSEBioGRID17070805 details
UBC_HUMANVPS36_MOUSEBioGRID15755741 details
UBC_HUMANSTAM2_MOUSEBioGRID12972556 details
UBC_HUMANSTAM1_MOUSEBioGRID12972556 details
UBC_HUMANRAG1_MOUSEBioGRID14671314 details
UBC_HUMANMELK_MOUSEBioGRID23747528 details
UBC_HUMANRNF25_MOUSEBioGRID10500182 details
UBC_HUMANUBP19_MOUSEBioGRID25088257 details
UBC_HUMANP4K2A_MOUSEBioGRID23146885 details
UBC_HUMANCYLD_MOUSEBioGRID18174161 details
UBC_HUMANZSWM2_MOUSEBioGRID16522193 details
UBC_HUMANHGS_MOUSEBioGRID12972556 details
UBC_HUMANADRM1_MOUSEBioGRID25666615 details
UBC_HUMANREV1_MOUSEBioGRID26795561 details
UBC_HUMANT53I2_MOUSEBioGRID30979779 31155706 details
UBC_HUMANSQSTM_MOUSEBioGRID31362587 details
UBC_HUMANUBP5_MOUSEMINT11689694 details
UBC_HUMANTRPV4_MOUSEMINT17110928 details
UBC_HUMANTRPC4_MOUSEMINT17110928 details
UBC_HUMANNEMO_MOUSEBioGRID, MINT19763089 19766637 22819327 details
UBC_HUMANBID_MOUSEMINT20392206 details
UBC_HUMANFZD4_MOUSEMINT20495530 details
UBC_HUMANSMAD3_MOUSEMINT22045334 details
UBC_HUMANSMAD7_MOUSEMINT22045334 details
UBC_HUMANFXL20_MOUSEBioGRID17803915 details
UBC_HUMANESR1_MOUSEBioGRID16055746 details
UBC_HUMANMIB2_MOUSEBioGRID15824097 details
UBC_HUMANITPR3_MOUSEBioGRID12421829 details
UBC_HUMANUFD1_MOUSEBioGRID12411482 details
UBC_HUMANNPL4_MOUSEBioGRID12411482 details
UBC_HUMANGRM1_MOUSEBioGRID22486777 details
UBC_HUMANPJA1_MOUSEBioGRID10500182 details
UBC_HUMANBRCA1_MOUSEBioGRID10500182 details
UBC_HUMANCOP1_MOUSEBioGRID12466024 details
UBC_HUMANUCHL5_MOUSEBioGRID25702872 details