Entity Details

Primary name TYSY_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP07607
EntryNameTYSY_MOUSE
FullNameThymidylate synthase
TaxID10090
Evidenceevidence at protein level
Length307
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesTyms

GO terms

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GOName
GO:0000900 translation repressor activity, mRNA regulatory element binding
GO:0003729 mRNA binding
GO:0004799 thymidylate synthase activity
GO:0005542 folic acid binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006231 dTMP biosynthetic process
GO:0006235 dTTP biosynthetic process
GO:0006417 regulation of translation
GO:0007568 aging
GO:0007623 circadian rhythm
GO:0009636 response to toxic substance
GO:0017148 negative regulation of translation
GO:0019048 modulation by virus of host process
GO:0019860 uracil metabolic process
GO:0032259 methylation
GO:0032570 response to progesterone
GO:0033189 response to vitamin A
GO:0034097 response to cytokine
GO:0035999 tetrahydrofolate interconversion
GO:0042493 response to drug
GO:0042803 protein homodimerization activity
GO:0045471 response to ethanol
GO:0048589 developmental growth
GO:0051216 cartilage development
GO:0051384 response to glucocorticoid
GO:0051593 response to folic acid
GO:0060574 intestinal epithelial cell maturation
GO:0097421 liver regeneration
GO:1901363 heterocyclic compound binding
GO:1990825 sequence-specific mRNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Mitochondrion inner membrane
Mitochondrion matrix
Nucleus

Domains

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DomainNameCategoryType
IPR000398 Thymidylate synthaseFamilyFamily
IPR020940 Thymidylate synthase, active siteSiteActive site
IPR023451 Thymidylate synthase/dCMP hydroxymethylase domainDomainDomain
IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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