Entity Details

Primary name RIR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP07742
EntryNameRIR1_MOUSE
FullNameRibonucleoside-diphosphate reductase large subunit
TaxID10090
Evidenceevidence at protein level
Length792
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesRrm1

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 ATP binding
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005971 ribonucleoside-diphosphate reductase complex
GO:0006206 pyrimidine nucleobase metabolic process
GO:0006260 DNA replication
GO:0008584 male gonad development
GO:0009263 deoxyribonucleotide biosynthetic process
GO:0010212 response to ionizing radiation
GO:0017076 purine nucleotide binding
GO:0021846 cell proliferation in forebrain
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0051290 protein heterotetramerization
GO:0060041 retina development in camera-type eye
GO:0061731 ribonucleoside-diphosphate reductase activity
GO:0097718 disordered domain specific binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000788 Ribonucleotide reductase large subunit, C-terminalDomainDomain
IPR005144 ATP-cone domainDomainDomain
IPR008926 Ribonucleotide reductase R1 subunit, N-terminalFamilyHomologous superfamily
IPR013346 Ribonucleotide reductase, class I , alpha subunitDomainDomain
IPR013509 Ribonucleotide reductase large subunit, N-terminalDomainDomain
IPR039718 Ribonucleoside-diphosphate reductase large subunitFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
RIR1_MOUSEKAT5_MOUSEBioGRID20159953 details
RIR1_MOUSERIR2_MOUSEBioGRID16861739 details