Entity Details

Primary name HS71B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP0DMV9
EntryNameHS71B_HUMAN
FullNameHeat shock 70 kDa protein 1B
TaxID9606
Evidenceevidence at protein level
Length641
SequenceStatuscomplete
DateCreated2015-05-27
DateModified2021-06-02

Ontological Relatives

GO terms

Show/Hide Table
GOName
GO:0001618 virus receptor activity
GO:0001664 G protein-coupled receptor binding
GO:0003723 RNA binding
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006402 mRNA catabolic process
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0016192 vesicle-mediated transport
GO:0016234 inclusion body
GO:0016235 aggresome
GO:0016607 nuclear speck
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0030308 negative regulation of cell growth
GO:0031072 heat shock protein binding
GO:0031396 regulation of protein ubiquitination
GO:0031397 negative regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0031982 vesicle
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032757 positive regulation of interleukin-8 production
GO:0032991 protein-containing complex
GO:0034599 cellular response to oxidative stress
GO:0034605 cellular response to heat
GO:0034620 cellular response to unfolded protein
GO:0042026 protein refolding
GO:0042826 histone deacetylase binding
GO:0043066 negative regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0044183 protein folding chaperone
GO:0045648 positive regulation of erythrocyte differentiation
GO:0046034 ATP metabolic process
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051787 misfolded protein binding
GO:0055131 C3HC4-type RING finger domain binding
GO:0060548 negative regulation of cell death
GO:0070062 extracellular exosome
GO:0070370 cellular heat acclimation
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0072562 blood microparticle
GO:0090063 positive regulation of microtubule nucleation
GO:0090084 negative regulation of inclusion body assembly
GO:1900034 regulation of cellular response to heat
GO:1901673 regulation of mitotic spindle assembly
GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
GO:1904813 ficolin-1-rich granule lumen
GO:1990904 ribonucleoprotein complex
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR013126 Heat shock protein 70 familyFamilyFamily
IPR018181 Heat shock protein 70, conserved siteSiteConserved site
IPR029047 Heat shock protein 70kD, peptide-binding domain superfamilyFamilyHomologous superfamily
IPR029048 Heat shock protein 70kD, C-terminal domain superfamilyFamilyHomologous superfamily
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

Show/Hide Table