Entity Details

Primary name HS90A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP07901
EntryNameHS90A_MOUSE
FullNameHeat shock protein HSP 90-alpha
TaxID10090
Evidenceevidence at protein level
Length733
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesHsp90aa1

GO terms

Show/Hide Table
GOName
GO:0001764 neuron migration
GO:0001934 positive regulation of protein phosphorylation
GO:0002134 UTP binding
GO:0002135 CTP binding
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0003729 mRNA binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0006809 nitric oxide biosynthetic process
GO:0006986 response to unfolded protein
GO:0007004 telomere maintenance via telomerase
GO:0009408 response to heat
GO:0009409 response to cold
GO:0009986 cell surface
GO:0010592 positive regulation of lamellipodium assembly
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016887 ATP hydrolysis activity
GO:0017098 sulfonylurea receptor binding
GO:0019903 protein phosphatase binding
GO:0021955 central nervous system neuron axonogenesis
GO:0030010 establishment of cell polarity
GO:0030235 nitric-oxide synthase regulator activity
GO:0030911 TPR domain binding
GO:0031396 regulation of protein ubiquitination
GO:0031526 brush border membrane
GO:0031625 ubiquitin protein ligase binding
GO:0032273 positive regulation of protein polymerization
GO:0032564 dATP binding
GO:0032728 positive regulation of interferon-beta production
GO:0032991 protein-containing complex
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034605 cellular response to heat
GO:0036126 sperm flagellum
GO:0042026 protein refolding
GO:0042307 positive regulation of protein import into nucleus
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043209 myelin sheath
GO:0044183 protein folding chaperone
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0044325 transmembrane transporter binding
GO:0045040 protein insertion into mitochondrial outer membrane
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045585 positive regulation of cytotoxic T cell differentiation
GO:0045793 positive regulation of cell size
GO:0046677 response to antibiotic
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048675 axon extension
GO:0050821 protein stabilization
GO:0051020 GTPase binding
GO:0051022 Rho GDP-dissociation inhibitor binding
GO:0051082 unfolded protein binding
GO:0051131 chaperone-mediated protein complex assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051973 positive regulation of telomerase activity
GO:0062023 collagen-containing extracellular matrix
GO:0070182 DNA polymerase binding
GO:0097110 scaffold protein binding
GO:0097226 sperm mitochondrial sheath
GO:0097524 sperm plasma membrane
GO:0097718 disordered domain specific binding
GO:0098586 cellular response to virus
GO:1902949 positive regulation of tau-protein kinase activity
GO:1903364 positive regulation of cellular protein catabolic process
GO:1903827 regulation of cellular protein localization
GO:1905323 telomerase holoenzyme complex assembly
GO:1990782 protein tyrosine kinase binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm
Melanosome
Mitochondrion
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001404 Heat shock protein Hsp90 familyFamilyFamily
IPR003594 Histidine kinase/HSP90-like ATPaseDomainDomain
IPR019805 Heat shock protein Hsp90, conserved siteSiteConserved site
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR020575 Heat shock protein Hsp90, N-terminalDomainDomain
IPR036890 Histidine kinase/HSP90-like ATPase superfamilyFamilyHomologous superfamily
IPR037196 HSP90, C-terminal domainFamilyHomologous superfamily

Diseases

Show/Hide Table