Entity Details

Primary name MYB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10242
EntryNameMYB_HUMAN
FullNameTranscriptional activator Myb
TaxID9606
Evidenceevidence at protein level
Length640
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMYB

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000278 mitotic cell cycle
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006338 chromatin remodeling
GO:0006355 regulation of transcription, DNA-templated
GO:0016363 nuclear matrix
GO:0032967 positive regulation of collagen biosynthetic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045624 positive regulation of T-helper cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0051574 positive regulation of histone H3-K9 methylation
GO:0060252 positive regulation of glial cell proliferation
GO:0070301 cellular response to hydrogen peroxide
GO:0071300 cellular response to retinoic acid
GO:0071636 positive regulation of transforming growth factor beta production
GO:1901533 negative regulation of hematopoietic progenitor cell differentiation
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1904899 positive regulation of hepatic stellate cell proliferation
GO:2000491 positive regulation of hepatic stellate cell activation
GO:2000845 positive regulation of testosterone secretion

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001005 SANT/Myb domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR012642 Transcription regulator Wos2-domainDomainDomain
IPR015395 C-myb, C-terminalDomainDomain
IPR017930 Myb domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MYB_HUMANFBXW7_MOUSEBioGRID19421138 21092141 details