Entity Details

Primary name ODP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10515
EntryNameODP2_HUMAN
FullNameDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length647
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesDLAT

GO terms

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GOName
GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005967 mitochondrial pyruvate dehydrogenase complex
GO:0006006 glucose metabolic process
GO:0006086 acetyl-CoA biosynthetic process from pyruvate
GO:0006090 pyruvate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0030431 sleep
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0045254 pyruvate dehydrogenase complex

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR000089 Biotin/lipoyl attachmentDomainDomain
IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domainDomainDomain
IPR003016 2-oxo acid dehydrogenase, lipoyl-binding siteSiteBinding site
IPR004167 Peripheral subunit-binding domainDomainDomain
IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexFamilyFamily
IPR011053 Single hybrid motifFamilyHomologous superfamily
IPR023213 Chloramphenicol acetyltransferase-like domain superfamilyFamilyHomologous superfamily
IPR036625 E3-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB03758 RadicicolDrugbanksmall molecule
DB03760 Dihydrolipoic AcidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink