Entity Details

Primary name PTPRF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10586
EntryNamePTPRF_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase F
TaxID9606
Evidenceevidence at protein level
Length1907
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRF

GO terms

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GOName
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006470 protein dephosphorylation
GO:0007155 cell adhesion
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0008201 heparin binding
GO:0016477 cell migration
GO:0031102 neuron projection regeneration
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035373 chondroitin sulfate proteoglycan binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044877 protein-containing complex binding
GO:0048679 regulation of axon regeneration
GO:0050839 cell adhesion molecule binding
GO:0070062 extracellular exosome
GO:0099560 synaptic membrane adhesion
GO:1900121 negative regulation of receptor binding

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions