Entity Details

Primary name EGR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08046
EntryNameEGR1_MOUSE
FullNameEarly growth response protein 1
TaxID10090
Evidenceevidence at protein level
Length533
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesEgr1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0002931 response to ischemia
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007611 learning or memory
GO:0007616 long-term memory
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0009749 response to glucose
GO:0010385 double-stranded methylated DNA binding
GO:0010628 positive regulation of gene expression
GO:0010942 positive regulation of cell death
GO:0014911 positive regulation of smooth muscle cell migration
GO:0030217 T cell differentiation
GO:0030509 BMP signaling pathway
GO:0032722 positive regulation of chemokine production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032868 response to insulin
GO:0032922 circadian regulation of gene expression
GO:0033233 regulation of protein sumoylation
GO:0035035 histone acetyltransferase binding
GO:0035914 skeletal muscle cell differentiation
GO:0042981 regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0044729 hemi-methylated DNA-binding
GO:0044849 estrous cycle
GO:0045475 locomotor rhythm
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046886 positive regulation of hormone biosynthetic process
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0060086 circadian temperature homeostasis
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071310 cellular response to organic substance
GO:0071480 cellular response to gamma radiation
GO:0071504 cellular response to heparin
GO:0071506 cellular response to mycophenolic acid
GO:0072110 glomerular mesangial cell proliferation
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0098759 cellular response to interleukin-8
GO:1901216 positive regulation of neuron death
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1902949 positive regulation of tau-protein kinase activity
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:2000182 regulation of progesterone biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR021839 Early growth response protein 1, C-terminalRepeatRepeat
IPR021849 Early growth response, N-terminalDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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