Entity Details

Primary name FCGR2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08101
EntryNameFCGR2_MOUSE
FullNameLow affinity immunoglobulin gamma Fc region receptor II
TaxID10090
Evidenceevidence at protein level
Length330
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesFcgr2b

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001811 negative regulation of type I hypersensitivity
GO:0002434 immune complex clearance
GO:0002638 negative regulation of immunoglobulin production
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin
GO:0004888 transmembrane signaling receptor activity
GO:0005576 extracellular region
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006911 phagocytosis, engulfment
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
GO:0009617 response to bacterium
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016064 immunoglobulin mediated immune response
GO:0016358 dendrite development
GO:0019772 low-affinity IgG receptor activity
GO:0019864 IgG binding
GO:0019865 immunoglobulin binding
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0021549 cerebellum development
GO:0030889 negative regulation of B cell proliferation
GO:0032456 endocytic recycling
GO:0032693 negative regulation of interleukin-10 production
GO:0033030 negative regulation of neutrophil apoptotic process
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043197 dendritic spine
GO:0044297 cell body
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0046330 positive regulation of JNK cascade
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0050765 negative regulation of phagocytosis
GO:0050766 positive regulation of phagocytosis
GO:0050776 regulation of immune response
GO:0050777 negative regulation of immune response
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0055037 recycling endosome
GO:0071219 cellular response to molecule of bacterial origin
GO:1901216 positive regulation of neuron death
GO:1902950 regulation of dendritic spine maintenance
GO:1904646 cellular response to amyloid-beta
GO:1905898 positive regulation of response to endoplasmic reticulum stress

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FCGR2_MOUSEDOK1_MOUSEBioGRID11970986 details
FCGR2_MOUSESHIP1_MOUSEMINT9973396 details