Entity Details

Primary name ODPB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11177
EntryNameODPB_HUMAN
FullNamePyruvate dehydrogenase E1 component subunit beta, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesPDHB

GO terms

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GOName
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005967 mitochondrial pyruvate dehydrogenase complex
GO:0006006 glucose metabolic process
GO:0006086 acetyl-CoA biosynthetic process from pyruvate
GO:0006090 pyruvate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0045254 pyruvate dehydrogenase complex
GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR005475 Transketolase-like, pyrimidine-binding domainDomainDomain
IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IIFamilyHomologous superfamily
IPR027110 Pyruvate dehydrogenase E1 component subunit betaFamilyFamily
IPR029061 Thiamin diphosphate-binding foldFamilyHomologous superfamily
IPR033248 Transketolase, C-terminal domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00119 Pyruvic acidDrugbanksmall molecule
DB00157 NADHDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink