Entity Details

Primary name ERR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11474
EntryNameERR1_HUMAN
FullNameSteroid hormone receptor ERR1
TaxID9606
Evidenceevidence at protein level
Length423
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesESRRA

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001650 fibrillar center
GO:0003700 DNA-binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005496 steroid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007005 mitochondrion organization
GO:0008270 zinc ion binding
GO:0015630 microtubule cytoskeleton
GO:0019904 protein domain specific binding
GO:0043565 sequence-specific DNA binding
GO:0045171 intercellular bridge
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR024178 Estrogen receptor/oestrogen-related receptorFamilyFamily
IPR027289 Oestrogen-related receptorFamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00197 TroglitazoneDrugbanksmall molecule
DB00255 DiethylstilbestrolDrugbanksmall molecule
DB01645 GenisteinDrugbanksmall molecule
DB04468 AfimoxifeneDrugbanksmall molecule
DB06732 beta-NaphthoflavoneDrugbanksmall molecule
DB06833 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINEDrugbanksmall molecule
DB07776 FlavoneDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink