Entity Details

Primary name MDHM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08249
EntryNameMDHM_MOUSE
FullNameMalate dehydrogenase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length338
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesMdh2

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0006107 oxaloacetate metabolic process
GO:0006108 malate metabolic process
GO:0006734 NADH metabolic process
GO:0009060 aerobic respiration
GO:0016020 membrane
GO:0016615 malate dehydrogenase activity
GO:0030060 L-malate dehydrogenase activity
GO:0042803 protein homodimerization activity
GO:0043209 myelin sheath
GO:0043621 protein self-association
GO:0046554 malate dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001236 Lactate/malate dehydrogenase, N-terminalDomainDomain
IPR001252 Malate dehydrogenase, active siteSiteActive site
IPR001557 L-lactate/malate dehydrogenaseFamilyFamily
IPR010097 Malate dehydrogenase, type 1FamilyFamily
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminalFamilyHomologous superfamily
IPR022383 Lactate/malate dehydrogenase, C-terminalDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions