Entity Details

Primary name CADH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12830
EntryNameCADH1_HUMAN
FullNameCadherin-1
TaxID9606
Evidenceevidence at protein level
Length882
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesCDH1

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007416 synapse assembly
GO:0008013 beta-catenin binding
GO:0009636 response to toxic substance
GO:0009898 cytoplasmic side of plasma membrane
GO:0010468 regulation of gene expression
GO:0015629 actin cytoskeleton
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
GO:0016342 catenin complex
GO:0016600 flotillin complex
GO:0021983 pituitary gland development
GO:0022408 negative regulation of cell-cell adhesion
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030198 extracellular matrix organization
GO:0030336 negative regulation of cell migration
GO:0030506 ankyrin binding
GO:0031175 neuron projection development
GO:0032794 GTPase activating protein binding
GO:0034332 adherens junction organization
GO:0035635 entry of bacterium into host cell
GO:0042307 positive regulation of protein import into nucleus
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043296 apical junction complex
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048471 perinuclear region of cytoplasm
GO:0050839 cell adhesion molecule binding
GO:0070062 extracellular exosome
GO:0071285 cellular response to lithium ion
GO:0071681 cellular response to indole-3-methanol
GO:0072659 protein localization to plasma membrane
GO:0098609 cell-cell adhesion
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Endosome
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000233 Cadherin, cytoplasmic domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR014868 Cadherin prodomainDomainDomain
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR030049 Cadherin-1FamilyFamily
IPR039808 CadherinFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CADH1_HUMANHAKAI_MOUSEMINT22252131 details