Entity Details

Primary name NFM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08553
EntryNameNFM_MOUSE
FullNameNeurofilament medium polypeptide
TaxID10090
Evidenceevidence at protein level
Length848
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesNefm

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0005102 signaling receptor binding
GO:0005198 structural molecule activity
GO:0005856 cytoskeleton
GO:0005882 intermediate filament
GO:0005883 neurofilament
GO:0008088 axo-dendritic transport
GO:0014069 postsynaptic density
GO:0015643 toxic substance binding
GO:0030424 axon
GO:0031133 regulation of axon diameter
GO:0031594 neuromuscular junction
GO:0033693 neurofilament bundle assembly
GO:0043005 neuron projection
GO:0043204 perikaryon
GO:0043209 myelin sheath
GO:0044877 protein-containing complex binding
GO:0045104 intermediate filament cytoskeleton organization
GO:0045105 intermediate filament polymerization or depolymerization
GO:0045110 intermediate filament bundle assembly
GO:0060052 neurofilament cytoskeleton organization
GO:0099160 postsynaptic intermediate filament cytoskeleton
GO:0099182 presynaptic intermediate filament cytoskeleton

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR002957 Keratin, type IFamilyFamily
IPR006821 Intermediate filament head, DNA-binding domainDomainDomain
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR027697 Neurofilament medium polypeptideFamilyFamily
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NFM_MOUSENEB2_MOUSEBioGRID28634551 30562941 details