Entity Details

Primary name KAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13861
EntryNameKAP2_HUMAN
FullNamecAMP-dependent protein kinase type II-alpha regulatory subunit
TaxID9606
Evidenceevidence at protein level
Length404
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesPRKAR2A

GO terms

Show/Hide Table
GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004862 cAMP-dependent protein kinase inhibitor activity
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0005952 cAMP-dependent protein kinase complex
GO:0007268 chemical synaptic transmission
GO:0007596 blood coagulation
GO:0008603 cAMP-dependent protein kinase regulator activity
GO:0010738 regulation of protein kinase A signaling
GO:0016020 membrane
GO:0019904 protein domain specific binding
GO:0030552 cAMP binding
GO:0031588 nucleotide-activated protein kinase complex
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0034199 activation of protein kinase A activity
GO:0034236 protein kinase A catalytic subunit binding
GO:0035556 intracellular signal transduction
GO:0043949 regulation of cAMP-mediated signaling
GO:0044853 plasma membrane raft
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:0071377 cellular response to glucagon stimulus
GO:0097546 ciliary base
GO:2000480 negative regulation of cAMP-dependent protein kinase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR003117 cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domainDomainDomain
IPR012198 cAMP-dependent protein kinase regulatory subunitFamilyFamily
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018488 Cyclic nucleotide-binding, conserved siteSiteConserved site
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB05798 GEM-231Drugbankbiotech

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink