Entity Details

Primary name GNAI2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08752
EntryNameGNAI2_MOUSE
FullNameGuanine nucleotide-binding protein G(i) subunit alpha-2
TaxID10090
Evidenceevidence at protein level
Length355
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesGnai2

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0007049 cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0016020 membrane
GO:0030335 positive regulation of cell migration
GO:0030425 dendrite
GO:0030496 midbody
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032930 positive regulation of superoxide anion generation
GO:0033864 positive regulation of NAD(P)H oxidase activity
GO:0035810 positive regulation of urine volume
GO:0035815 positive regulation of renal sodium excretion
GO:0044297 cell body
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045955 negative regulation of calcium ion-dependent exocytosis
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0046872 metal ion binding
GO:0050805 negative regulation of synaptic transmission
GO:0051301 cell division
GO:0051924 regulation of calcium ion transport
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0140199 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
GO:1903614 negative regulation of protein tyrosine phosphatase activity
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR001408 G-protein alpha subunit, group IFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

3 interactions