Entity Details

Primary name RPB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP08775
EntryNameRPB1_MOUSE
FullNameDNA-directed RNA polymerase II subunit RPB1
TaxID10090
Evidenceevidence at protein level
Length1970
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesPolr2a

GO terms

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GOName
GO:0000791 euchromatin
GO:0001046 core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005737 cytoplasm
GO:0006353 DNA-templated transcription, termination
GO:0006366 transcription by RNA polymerase II
GO:0008022 protein C-terminus binding
GO:0014070 response to organic cyclic compound
GO:0019900 kinase binding
GO:0031625 ubiquitin protein ligase binding
GO:0033120 positive regulation of RNA splicing
GO:0046872 metal ion binding
GO:0071453 cellular response to oxygen levels
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000684 RNA polymerase II, heptapeptide repeat, eukaryoticRepeatRepeat
IPR000722 RNA polymerase, alpha subunitDomainDomain
IPR006592 RNA polymerase, N-terminalDomainDomain
IPR007066 RNA polymerase Rpb1, domain 3DomainDomain
IPR007073 RNA polymerase Rpb1, domain 7DomainDomain
IPR007075 RNA polymerase Rpb1, domain 6DomainDomain
IPR007080 RNA polymerase Rpb1, domain 1DomainDomain
IPR007081 RNA polymerase Rpb1, domain 5DomainDomain
IPR007083 RNA polymerase Rpb1, domain 4DomainDomain
IPR038120 RNA polymerase Rpb1, funnel domain superfamilyFamilyHomologous superfamily
IPR038593 RNA polymerase Rpb1, domain 7 superfamilyFamilyHomologous superfamily
IPR042102 RNA polymerase Rpb1, domain 3 superfamilyFamilyHomologous superfamily

Diseases

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